About.
The story
Trialgrids was built by Mehmet Şahin, a clinical research professional based in Gaziantep, Turkey, with 13 years of experience in bioequivalence and bioavailability (BE/BA) studies.
The tools came out of a familiar frustration: the daily friction of working in BE/BA research. Generating randomization lists in Excel. Building tube labels in Word with copy-paste-replace cycles. Manually counting samples for shipment. Writing the same time table from scratch every time a new protocol arrived.
Each task takes minutes, but multiplied across studies, subjects, periods, and timepoints, those minutes become hours. Hours that should go into actual research.
After watching this play out across enough studies, the question became: why is there no simple, fast, free tool that does any of this? The answer turned out to be that somebody had to build one.
The philosophy
Trialgrids is built on three principles.
Privacy-first. Every tool runs entirely in your browser. No accounts. No uploads. No servers receiving your data. When you close the tab, the data in memory is gone. This isn't a marketing claim — it's a technical fact about how the tools are written. If a malicious actor compromised our infrastructure tomorrow, they would find nothing about your studies, because nothing is there.
Documentation aid, not a clinical system. Trialgrids generates documents that help with documentation work. It is deliberately not a Clinical Data Management System (CDMS), not an Electronic Data Capture (EDC) tool, and not a substitute for your institution's validated systems. The line is intentional — building those systems requires regulatory validation that an indie project cannot deliver responsibly.
Free to use. The tools are free for individual researchers, study coordinators, biostatisticians, small CROs, and investigator sites. No paywall. No “free trial” with hidden conversions. If a tool helps you, use it.
The toolkit
Six tools live today, each targeting a specific friction point:
- Randomization Lists — Generate block randomization schedules with allocation ratios. Outputs audit-ready PDFs with timestamps, parameters, and seed values for reproducibility. Used at study setup before subject enrollment begins.
- Schedule of Assessments — Build SPIRIT-compliant time tables for trials. Add visits, mark assessments, generate the kind of grid that appears in every protocol synopsis.
- Meal Intake Logs — Track meal compliance across study periods. Fasting confirmation, standardized meals, post-dose feeding — the timing constraints that BE/BA studies depend on.
- Sample Shipment Counts — Calculate exact tube counts for bioanalytical lab shipments. Handles master + backup aliquot schemes, dropouts, did-not-start subjects, and lost samples. Outputs an audit-ready PDF for shipping documentation.
- Tube Label Generator — Generate printable tube labels formatted for Tanex TW-2052 sheets. Separates blood tube and plasma labels onto different sheets, tight-packs labels with no waste between timepoints, and inserts point-transition separator labels for personnel guidance. Replaces 4-6 hours of manual Word work in seconds.
- Adverse Event Form — Generate printable AE forms for clinical documentation. Fill in the volunteer's details at the bedside on phone or tablet, export a clean PDF, print, sign, and attach to the CRF. Replaces 5-10 minutes of manual paper form-filling per event.
Each tool is intentionally narrow. The randomization tool does randomization, not subject management. The sample shipment tool counts samples, not whole study logistics. Doing one thing well, and getting out of the way.
What Trialgrids is not
Trialgrids does not:
- Handle patient-identifying information
- Store subject data on any server
- Replace your institution's validated systems
- Integrate with EDC or CDMS platforms
- Provide regulatory consulting
If your study requires a CDMS, look at OpenClinica, Castor, or REDCap. If you need a full eClinical platform, look at Medidata Rave or Veeva Vault. Trialgrids exists in the spaces those platforms don't bother filling — the small, manual, repetitive tasks that nobody else has thought worth automating.
Coming soon
The roadmap is short, intentional, and shaped by what BE/BA researchers actually need:
- CRF Template Generator — Standard case report forms (demographic, vital signs, sample collection, adverse event, concomitant medication) generated with study-specific headers. PDF and Word output planned.
- Sample Size Calculator — For BE/BA crossover designs with EMA and FDA criteria. Scaled average bioequivalence support. Designed for protocol planning.
New tools are released only when they meet the same bar: a real friction point that a small browser-based tool can genuinely solve.
Open questions, welcomed
Trialgrids is built by a researcher who still works in the field, for researchers who work in the field. If you spot a missing tool, a friction point we haven't addressed, or a feature that would change how a study runs — write in.
Email: info@trialgrids.com
Response: within 1 business day
The tools improve when the people using them push back.